ω3 fatty acid metabolite, 12‐hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α-Reference-Cited by-同舟云学术

ω3 fatty acid metabolite, 12‐hydroxyeicosapentaenoic acid, alleviates contact hypersensitivity by downregulation of CXCL1 and CXCL2 gene expression in keratinocytes via retinoid X receptor α

Published:2021-03-22 Issue:4 Volume:35 Page:
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Saika Azusa¹²,Nagatake Takahiro¹,Hirata So‐ichiro¹,Sawane Kento¹²³,Adachi Jun⁴,Abe Yuichi⁴⁵,Isoyama Junko⁴,Morimoto Sakiko¹,Node Eri¹,Tiwari Prabha¹,Hosomi Koji¹,Matsunaga Ayu¹⁶,Honda Tetsuya⁷⁸,Tomonaga Takeshi⁴,Arita Makoto⁹¹⁰¹¹,Kabashima Kenji⁷,Kunisawa Jun¹²¹²¹³¹⁴

Affiliation:

1. Laboratory of Vaccine Materials Center for Vaccine and Adjuvant Research and Laboratory of Gut Environmental SystemNational Institutes of Biomedical InnovationHealth and Nutrition (NIBIOHN) Osaka Japan

2. Graduate School of Pharmaceutical Sciences Osaka University Osaka Japan

3. Nippon Flour Mills Co., LtdInnovation Center Atsugi Japan

4. Laboratory of Proteome Research and Laboratory of Proteomics for Drug Discovery NIBIOHN Osaka Japan

5. Division of Molecular Diagnosis Aichi Cancer Center Research Institute Nagoya Japan

6. Department of Food and Life Science School of Life and Environmental Science Azabu University Sagamihara Japan

7. Department of Dermatology Kyoto University Graduate School of Medicine Kyoto Japan

8. Department of Dermatology Hamamatsu University School of Medicine Shizuoka Japan

9. Division of Physiological Chemistry and Metabolism Faculty of Pharmacy Keio University Tokyo Japan

10. Laboratory for Metabolomics RIKEN Center for Integrative Medical Sciences Yokohama Japan

11. Cellular and Molecular Epigenetics Laboratory Graduate School of Medical Life Science Yokohama City University Yokohama Japan

12. Department of Microbiology and Immunology Kobe University Graduate School of Medicine Kobe Japan

13. International Research and Development Center for Mucosal VaccinesThe Institute of Medical ScienceThe University of Tokyo Tokyo Japan

14. Graduate School of Medicine Graduate School of DentistryOsaka University Suita Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

University of Tokyo

Ono Medical Research Foundation

Canon Foundation in Europe

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.202001687R

Reference81 articles.

1. Early immune events in the induction of allergic contact dermatitis

2. Prevalence of contact allergy in the general population: A systematic review and meta-analysis

3. Immunological mechanisms of contact hypersensitivity in mice

4. Update of Immune Events in the Murine Contact Hypersensitivity Model: Toward the Understanding of Allergic Contact Dermatitis

5. Cytokines and Chemokines in Irritant Contact Dermatitis

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