Dihydropyrimidine Dehydrogenase Deficiency, a Pharmacogenetic Syndrome Associated with Potentially Life-Threatening Toxicity Following 5-Fluorouracil Administration

Author:

Ezzeldin Hany,Diasio Robert

Publisher

Elsevier BV

Subject

Gastroenterology,Oncology

Reference70 articles.

1. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies;Lazarou;JAMA,1998

2. Toxicity of fluorouracil in patients with advanced colorectal cancer: effect of administration schedule and prognostic factors. Meta-Analysis Group In Cancer;J Clin Oncol,1998

3. Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil;Johnson;Adv Enzyme Regul,2001

4. Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene;van Kuilenburg;Clin Cancer Res,2000

5. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile;Heggie;Cancer Res,1987

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