Structure-Guided Deimmunization of Therapeutic Proteins
Author:
Affiliation:
1. Department of Computer Science, Dartmouth College, Hanover, New Hampshire.
2. Thayer School of Engineering, Dartmouth College, Hanover, New Hampshire.
Publisher
Mary Ann Liebert Inc
Subject
Computational Theory and Mathematics,Computational Mathematics,Genetics,Molecular Biology,Modelling and Simulation
Link
http://www.liebertpub.com/doi/pdf/10.1089/cmb.2012.0251
Reference43 articles.
1. A graph-theory algorithm for rapid protein side-chain prediction
2. Computational structure-based redesign of enzyme activity
3. De Novo Protein Design: Fully Automated Sequence Selection
4. Reducing risk, improving outcomes: Bioengineering less immunogenic protein therapeutics
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