Human Vascular Wall Microfluidic Model for Preclinical Evaluation of Drug-Induced Vascular Injury

Author:

Ersland Erik1,Ebrahim Neven123ORCID,Mwizerwa Olive1,Oba Takahiro4,Oku Keisuke4,Nishino Masafumi4,Hikimoto Daichi4,Miyoshi Hayato4,Tomotoshi Kimihiko4,Rahmanian Omid12,Ekwueme Emmanuel12,Neville Craig12,Sundback Cathryn12ORCID

Affiliation:

1. Department of Surgery, Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

2. Harvard Medical School, Boston, Massachusetts, USA.

3. Department of Anatomy and Embryology, Mansoura University, Mansoura, Egypt.

4. Bioscience and Engineering Laboratories, FUJIFILM Corporation, Kanagawa, Japan.

Publisher

Mary Ann Liebert Inc

Subject

Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Reference51 articles.

1. 1. CDER U.S. Food and Drug Administration. Letter of support for drug-induced vascular injury (DIVI) biomarker(s). U.S. Food and Drug, Silver Spring, MD, 2016.

2. Nonclinical Safety Biomarkers of Drug-induced Vascular Injury

3. Review of Cardiovascular Findings in Humans Treated with Minoxidil

4. Translation Strategy for the Qualification of Drug-induced Vascular Injury Biomarkers

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