Single Hepatic Venous Injection of Liver-Specific Naked Plasmid Vector Expressing Human UGT1A1 Leads to Long-Term Correction of Hyperbilirubinemia and Prevention of Chronic Bilirubin Toxicity in Gunn Rats
Author:
Affiliation:
1. Department of Pediatrics, Waisman Center, University of Wisconsin-Madison, Madison, WI 53705.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2005.16.985
Reference39 articles.
1. Regulation of the human bilirubin UDP-glucuronosyltransferase gene
2. Hypothesis: naked plasmid DNA is taken up by cellsin vivo by a receptor-mediated process
3. Selective Repopulation of Normal Mouse Liver by Hepatocytes Transducedin Vivowith Recombinant Adeno-Associated Virus
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2. Correction of Hyperbilirubinemia in Gunn Rats by Surgical Delivery of Low Doses of Helper-Dependent Adenoviral Vectors;Human Gene Therapy Methods;2014-06
3. Sustained Reduction of Hyperbilirubinemia in Gunn Rats After Adeno-Associated Virus-Mediated Gene Transfer of Bilirubin UDP-Glucuronosyltransferase Isozyme 1A1 to Skeletal Muscle;Human Gene Therapy;2012-10
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