Activation of cAMP-Responsive-Element-Binding Protein by PI3 Kinase and p38 MAPK Is Essential for Elevated Expression of Transforming Growth Factor β2 in Cancer Cells-Reference-Cited by-同舟云学术

Activation of cAMP-Responsive-Element-Binding Protein by PI3 Kinase and p38 MAPK Is Essential for Elevated Expression of Transforming Growth Factor β2 in Cancer Cells

Published:2010-09 Issue:9 Volume:30 Page:677-681
ISSN:1079-9907
Container-title:Journal of Interferon & Cytokine Research
language:en
Short-container-title:Journal of Interferon & Cytokine Research

Author:

Wan Youzhong¹²,Yang Maojing¹,Kolattukudy Sunny¹,Stark George R.¹²,Lu Tao¹

Affiliation:

1. Department of Molecular Genetics, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

2. Department of Genetics, Case Western Reserve University, Cleveland, Ohio.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Cell Biology,Immunology

Link

http://www.liebertpub.com/doi/pdf/10.1089/jir.2009.0117

Reference14 articles.

1. p38 MAP-Kinases pathway regulation, function and role in human diseases

2. CREB Is a Regulatory Target for the Protein Kinase Akt/PKB

3. Drug discovery approaches targeting the PI3K/Akt pathway in cancer

4. Secreted transforming growth factor 2 activates NF- B, blocks apoptosis, and is essential for the survival of some tumor cells

5. Secretion of cytokines and growth factors as a general cause of constitutive NFκB activation in cancer

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