Drug discovery approaches targeting the PI3K/Akt pathway in cancer
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2008246.pdf
Reference120 articles.
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3. Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PRJ, Reese CB et al. (1997). Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B. Curr Biol 7: 261–269.
4. Arico S, Pattingre S, Bauvy C, Gane P, Barbat A, Codogno P et al. (2002). Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. J Biol Chem 277: 27613–27621.
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