Characterization and Functional Analysis of CD44v6.CAR T Cells Endowed with a New Low-Affinity Nerve Growth Factor Receptor-Based Spacer-Reference-Cited by-同舟云学术

Characterization and Functional Analysis of CD44v6.CAR T Cells Endowed with a New Low-Affinity Nerve Growth Factor Receptor-Based Spacer

Published:2021-07-01 Issue:13-14 Volume:32 Page:744-760
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Stornaiuolo Anna¹,Valentinis Barbara¹,Sirini Camilla¹²³,Scavullo Cinzia¹,Asperti Claudia¹,Zhou Dan¹,Martinez De La Torre Yeny¹,Corna Stefano¹,Casucci Monica²,Porcellini Simona¹,Traversari Catia¹

Affiliation:

1. Research Department, AGC Biologics SpA (Formerly MolMed SpA), Milan, Italy

2. Innovative Immunotherapies Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCSS San Raffaele Scientific Institute, Milan, Italy; and

3. Vita-Salute San Raffaele University, Milan, Italy.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2020.216

Reference50 articles.

1. Targeting tumours with genetically enhanced T lymphocytes

2. Adoptive immunotherapy: Engineering T cell responses as biologic weapons for tumor mass destruction

3. Prolonged Persistence of Chimeric Antigen Receptor (CAR) T Cell in Adoptive Cancer Immunotherapy: Challenges and Ways Forward

4. Generation of clinical-grade CD19-specific CAR-modified CD8+ memory stem cells for the treatment of human B-cell malignancies

5. The pharmacology of second-generation chimeric antigen receptors

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