Inhibition of ALK-Signaling Overcomes STRN-ALK-Induced Downregulation of the Sodium Iodine Symporter and Restores Radioiodine Uptake in Thyroid Cells
Author:
Affiliation:
1. Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Publisher
Mary Ann Liebert Inc
Subject
Endocrinology,Endocrinology, Diabetes and Metabolism
Link
https://www.liebertpub.com/doi/pdf/10.1089/thy.2022.0533
Reference38 articles.
1. Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation
2. Sustained ERK inhibition maximizes responses of BrafV600E thyroid cancers to radioiodine
3. Selumetinib-Enhanced Radioiodine Uptake in Advanced Thyroid Cancer
4. Redifferentiation of Iodine-Refractory BRAF V600E-Mutant Metastatic Papillary Thyroid Cancer with Dabrafenib
5. Targeted Therapy in Advanced Thyroid Cancer to Resensitize Tumors to Radioactive Iodine
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