Development and Validation of a Secondary Screening Assay for TRPM8 Antagonists Using QPatch HT-Reference-Cited by-同舟云学术

Development and Validation of a Secondary Screening Assay for TRPM8 Antagonists Using QPatch HT

Published:2010-02 Issue:1 Volume:8 Page:63-72
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Beck Edward J.¹,Hutchinson Tasha L.¹,Qin Ning¹,Flores Christopher M.¹,Liu Yi¹

Affiliation:

1. Analgesics Drug Discovery, East Coast Research and Early Development, Johnson and Johnson Pharmaceutical Research and Development, L.L.C., Spring House, Pennsylvania.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2009.0214

Reference13 articles.

1. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

2. High-throughput electrophysiology: an emerging paradigm for ion-channel screening and physiology

3. QPatch: the past, present and future of automated patch clamp

4. Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels

5. Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance

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