A Fluorescence-Based High-Throughput Screening Assay for the Identification of T-Type Calcium Channel Blockers-Reference-Cited by-同舟云学术

A Fluorescence-Based High-Throughput Screening Assay for the Identification of T-Type Calcium Channel Blockers

Published:2009-06 Issue:3 Volume:7 Page:266-280
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Belardetti Francesco¹,Tringham Elizabeth²,Eduljee Cyrus²,Jiang Xinpo²,Dong Haiheng³,Hendricson Adam⁴,Shimizu Yoko⁵,Janke Diana L.⁶,Parker David²,Mezeyova Janette²,Khawaja Afsheen²,Pajouhesh Hassan²,Fraser Robert A.⁵,Arneric Stephen P.⁷,Snutch Terrance P.⁸

Affiliation:

1. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: Panora Pharmaceuticals Inc., Vancouver, British Columbia, Canada.

2. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada.

3. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: WuXi Pharmatech, Shanghai, China.

4. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: Bristol-Myers Squibb, Wallingford, Connecticut.

5. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: Centre for Drug Research and Development, University of British Columbia, Vancouver, British Columbia, Canada.

6. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: WorkSafeBC, Burnaby, British Columbia, Canada.

7. Neuromed Pharmaceuticals Ltd., Vancouver, British Columbia, Canada. Present address: Eli Lilly & Company, Indianapolis, Indiana.

8. Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2009.191

Reference63 articles.

1. Structure and Regulation of Voltage-Gated Ca2+ Channels

2. International Union of Pharmacology. XLVIII. Nomenclature and Structure-Function Relationships of Voltage-Gated Calcium Channels

3. Molecular characterization of a neuronal low-voltage-activated T-type calcium channel

4. Cloning and Characterization of α1H From Human Heart, a Member of the T-Type Ca 2+ Channel Gene Family

5. Molecular and Functional Characterization of a Family of Rat Brain T-type Calcium Channels

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