Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2by Redox Cycling in Reducing Environments-Reference-Cited by-同舟云学术

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Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2by Redox Cycling in Reducing Environments

Published:2010-04 Issue:2 Volume:8 Page:152-174
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Soares Karina M.¹,Blackmon Nicole¹,Shun Tong Ying¹,Shinde Sunita N.¹,Takyi Harold K.¹,Wipf Peter¹²,Lazo John S.¹³,Johnston Paul A.¹³

Affiliation:

1. Pittsburgh Molecular Library Screening Center, Drug Discovery Institute, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

2. Department of Chemistry, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

3. Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2009.0247

Reference44 articles.

1. The oxidative mechanism of action of ortho-quinone inhibitors of protein-tyrosine phosphatase α is mediated by hydrogen peroxide

2. Redox Regulation of Cdc25B by Cell-Active Quinolinediones

3. Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents

4. Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B

5. Radical-Induced Oxidation of Dithiothreitol in Acidic Oxygenated Aqueous Solution: A Chain Reaction

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