Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B-Reference-Cited by-同舟云学术

Computational design, synthesis and biological evaluation of para-quinone-based inhibitors for redox regulation of the dual-specificity phosphatase Cdc25B

Published:2008 Issue:18 Volume:6 Page:3256
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Keinan Shahar,Paquette William D.,Skoko John J.,Beratan David N.,Yang Weitao,Shinde Sunita,Johnston Paul A.,Lazo John S.,Wipf Peter

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2008/OB/B806712K

Reference45 articles.

1. Inhibition of Cdc25 Phosphatases by Indolyldihydroxyquinones

2. CDC25 Phosphatases as Potential Human Oncogenes

3. Modeling of Cdc25B Dual Specifity Protein Phosphatase Inhibitors: Docking of Ligands and Enzymatic Inhibition Mechanism

4. Redox Regulation of Cdc25B by Cell-Active Quinolinediones

5. Fluorinated quinoid inhibitor: possible `pure' arylator predicted by the simple theoretical calculation

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