<i>In Vitro</i> and <i>In Silico</i> Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells-Reference-Cited by-同舟云学术

In Vitro and In Silico Study to Assess Toxic Mechanisms of Hybrid Molecules of Quinone-Benzocaine as Plastoquinone Analogues in Breast Cancer Cells

Published:2022-08-15 Issue:34 Volume:7 Page:30250-30264
ISSN:2470-1343
Container-title:ACS Omega
language:en
Short-container-title:ACS Omega

Author:

Yilmaz Goler Ayse Mine¹,Jannuzzi Ayse Tarbin²,Bayrak Nilüfer³,Yıldız Mahmut⁴^ORCID,Yıldırım Hatice³,Otsuka Masami⁵⁶^ORCID,Fujita Mikako⁵,Radwan Mohamed O.⁵⁷,TuYuN Amaç Fatih⁸^ORCID

Affiliation:

1. Department of Biochemistry, School of Medicine/Genetic and Metabolic Diseases Research and Investigation Center, Marmara University, 34854 Istanbul, Turkey

2. Department of Pharmaceutical Toxicology, Faculty of Pharmacy, Istanbul University, 34126 Istanbul, Turkey

3. Department of Chemistry, Faculty of Engineering, Istanbul University-Cerrahpasa, Avcılar, 34320 Istanbul, Turkey

4. Department of Chemistry, Gebze Technical University, Gebze 41400, Kocaeli, Turkey

5. Medicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto, Kumamoto 862-0973, Japan

6. Department of Drug Discovery, Science Farm Ltd., 1-7-30 Kuhonji, Chuo-ku, Kumamoto, Kumamoto 862-0976, Japan

7. Chemistry of Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Centre, Dokki, Cairo 12622, Egypt

8. Department of Chemistry, Faculty of Science, Istanbul University, Fatih, 34126 Istanbul, Turkey

Funder

Istanbul ?niversitesi-Cerrahpasa

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsomega.2c03428

Reference66 articles.

1. Parallel Synthesis and Cytotoxicity Evaluation of a Polyamine−Quinone Conjugates Library

2. A novel aromatic amide derivative SY-65 co-targeted tubulin and histone deacetylase 1 with potent anticancer activity in vitro and in vivo