Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2-Reference-Cited by-同舟云学术

Hydrogen Sulfide Protects Against Cellular Senescence via S-Sulfhydration of Keap1 and Activation of Nrf2

Published:2013-05-20 Issue:15 Volume:18 Page:1906-1919
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Yang Guangdong¹²,Zhao Kexin¹²,Ju Youngjun¹²,Mani Sarathi¹³,Cao Qiuhui¹⁴,Puukila Stephanie³,Khaper Neelam⁵,Wu Lingyun¹⁴,Wang Rui¹³

Affiliation:

1. Cardiovascular and Metabolic Research Unit, Lakehead University, Ontario, Canada.

2. The School of Kinesiology, Lakehead University, Ontario, Canada.

3. Department of Biology, Lakehead University, Ontario, Canada.

4. Department of Health Sciences, Lakehead University, Ontario, Canada.

5. Northern Ontario School of Medicine, Lakehead University, Ontario, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

http://www.liebertpub.com/doi/pdf/10.1089/ars.2012.4645

Reference45 articles.

1. The signals and pathways activating cellular senescence

2. Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

3. Replicative Senescence and Oxidant-Induced Premature Senescence: Beyond the Control of Cell Cycle Checkpoints

4. Early onset senescence occurs when fibroblasts lack the glutamate–cysteine ligase modifier subunit

5. Integrated Stress Response Modulates Cellular Redox State via Induction of Cystathionine γ-Lyase

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