Locally Targeted Cardiac Gene Delivery by AAV Microbubble Destruction in a Large Animal Model
Author:
Affiliation:
1. Department of Internal Medicine III, Cardiology, Heidelberg University Hospital, University of Heidelberg, Heidelberg, Germany.
2. Department of Medicine, Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania.
Publisher
Mary Ann Liebert Inc
Subject
Genetics (clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2015.120
Reference23 articles.
1. Adeno-Associated Virus Vector Delivery to the Heart
2. Heart Failure Gene Therapy
3. Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)
4. AAV6. ARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
5. Cardiac AAV9-S100A1 Gene Therapy Rescues Post-Ischemic Heart Failure in a Preclinical Large Animal Model
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