Genetic Modification of T Cells with Chimeric Antigen Receptors: A Laboratory Manual
Author:
Affiliation:
1. Center for Molecular Medicine Cologne, University of Cologne, and Department I of Internal Medicine, University Hospital Cologne, Cologne, Germany.
Publisher
Mary Ann Liebert Inc
Subject
Genetics (clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2017.083
Reference33 articles.
1. The growing world of CAR T cell trials: a systematic review
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3. Specific activation and targeting of cytotoxic lymphocytes through chimeric single chains consisting of antibody-binding domains and the gamma or zeta subunits of the immunoglobulin and T-cell receptors.
4. Tumor-Specific T Cell Activation by Recombinant Immunoreceptors: CD3ζ Signaling and CD28 Costimulation Are Simultaneously Required for Efficient IL-2 Secretion and Can Be Integrated Into One Combined CD28/CD3ζ Signaling Receptor Molecule
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