Optimization of Electroporation-Enhanced Intradermal Delivery of DNA Vaccine Using a Minimally Invasive Surface Device-Reference-Cited by-同舟云学术

Optimization of Electroporation-Enhanced Intradermal Delivery of DNA Vaccine Using a Minimally Invasive Surface Device

Published:2012-06 Issue:3 Volume:23 Page:157-168
ISSN:1946-6536
Container-title:Human Gene Therapy Methods
language:en
Short-container-title:Human Gene Therapy Methods

Author:

Lin Feng¹,Shen Xuefei¹,Kichaev Gleb¹,Mendoza Janess M.¹,Yang Maria¹,Armendi Philip¹,Yan Jian¹,Kobinger Gary P.²,Bello Alexander²,Khan Amir S.¹,Broderick Kate E.¹,Sardesai Niranjan Y.¹

Affiliation:

1. Inovio Pharmaceuticals, Blue Bell, PA 19422.

2. Special Pathogens, National Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Genetics (clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2011.209

Reference49 articles.

1. In Vivo Electroporation Enhances the Immunogenicity of Hepatitis C Virus Nonstructural 3/4A DNA by Increased Local DNA Uptake, Protein Expression, Inflammation, and Infiltration of CD3+ T Cells

2. Cutaneous vaccination: the skin as an immunologically active tissue and the challenge of antigen delivery

3. Electroporation improves the efficacy of DNA vaccines in large animals

4. Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery

5. DNA vaccination and gene therapy: optimization and delivery for cancer therapy

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