Diffusive delivery of plasmid DNA using zwitterionic carboxyalkyl poly(1-vinylimidazole) into skeletal muscle <i>in vivo</i>-Reference-Cited by-同舟云学术

Diffusive delivery of plasmid DNA using zwitterionic carboxyalkyl poly(1-vinylimidazole) into skeletal muscle in vivo

Published:2024 Issue:15 Volume:12 Page:3947-3955
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Misaizu Ren¹,Endo-Takahashi Yoko²,Nirasawa Kei²,Negishi Yoichi²,Asayama Shoichiro¹^ORCID

Affiliation:

1. Department of Applied Chemistry, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, Japan

2. School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, 1432-1 Horinouchi, Hachioji, Tokyo 192-0392, Japan

Abstract

Zwitterionic carboxyalkyl poly(1-vinylimidazole), CA1(7)-PVIm, formed the polyion complex (PIC) with plasmid DNA (pDNA), leading to the diffusive delivery of the pDNA into skeletal muscle in vivo.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D4BM00510D

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