Glycopolycation–DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution-Reference-Cited by-同舟云学术

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Glycopolycation–DNA Polyplex Formulation N/P Ratio Affects Stability, Hemocompatibility, and in Vivo Biodistribution

Published:2019-03-28 Issue:4 Volume:20 Page:1530-1544
ISSN:1525-7797
Container-title:Biomacromolecules
language:en
Short-container-title:Biomacromolecules

Author:

Phillips Haley R.¹,Tolstyka Zachary P.¹,Hall Bryan C.²,Hexum Joseph K.¹,Hackett Perry B.²,Reineke Theresa M.¹^ORCID

Affiliation:

1. Center for Genome Engineering and Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States

2. Center for Genome Engineering and Department of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, Minnesota 55455, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

NIH Office of the Director

National Institute of Child Health and Human Development

Camille and Henry Dreyfus Foundation

Genomics Center, University of Minnesota

Special Coagulation Clinic, Fairview Hospital

Publisher

American Chemical Society (ACS)

Subject

Materials Chemistry,Polymers and Plastics,Biomaterials,Bioengineering

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.biomac.8b01704

Reference78 articles.

1. Nucleic-acid based gene therapeutics: delivery challenges and modular design of nonviral gene carriers and expression cassettes to overcome intracellular barriers for sustained targeted expression

2. Polymer gene delivery: overcoming the obstacles

3. Gene therapy as a new treatment option for inherited monogenic diseases

4. Advances in understanding and treating dystrophic epidermolysis bullosa

5. Barriers to and new approaches for gene therapy and gene delivery in cystic fibrosis

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