Efficient Production of Dual Recombinant Adeno-Associated Viral Vectors for Factor VIII Delivery-Reference-Cited by-同舟云学术

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Efficient Production of Dual Recombinant Adeno-Associated Viral Vectors for Factor VIII Delivery

Published:2014-08 Issue:4 Volume:25 Page:261-268
ISSN:1946-6536
Container-title:Human Gene Therapy Methods
language:en
Short-container-title:Human Gene Therapy Methods

Author:

Wang Qizhao¹,Dong Biao¹,Firrman Jenni¹,Roberts Sean¹,Moore Andrea Rossi¹,Cao Wenjing¹,Diao Yong²,Kapranov Philipp²,Xu Ruian²,Xiao Weidong¹³⁴

Affiliation:

1. Sol Sherry Thrombosis Research Center, Temple University, Philadelphia, PA 19140.

2. School of Biomedical Sciences, Huaqiao University, Quanzhou, Fujian 362021, China.

3. Cardiovascular Research Center, Temple University, Philadelphia, PA 19140.

4. Department of Microbiology and Immunology, Temple University, Philadelphia, PA 19140.

Publisher

Mary Ann Liebert Inc

Subject

Genetics(clinical),Pharmacology,Genetics,Applied Microbiology and Biotechnology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hgtb.2014.093

Reference41 articles.

1. Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

2. Coexpression of factor VIII heavy and light chain adeno-associated viral vectors produces biologically active protein

3. Expression of Human Factor VIII by Splicing between Dimerized AAV Vectors

4. The Enhancing Effects of the Light Chain on Heavy Chain Secretion in Split Delivery of Factor VIII Gene

5. Enhanced Factor VIII Heavy Chain for Gene Therapy of Hemophilia A

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