The Peptide Nucleic Acid Targeted to a Regulatory Sequence of the Translocated c-myc Oncogene in Burkitt's Lymphoma Lacks Immunogenicity: Follow-Up Characterization of PNAEμ-NLS-Reference-Cited by-同舟云学术

The Peptide Nucleic Acid Targeted to a Regulatory Sequence of the Translocated c-myc Oncogene in Burkitt's Lymphoma Lacks Immunogenicity: Follow-Up Characterization of PNAEμ-NLS

Published:2007-03 Issue:1 Volume:17 Page:146-150
ISSN:1545-4576
Container-title:Oligonucleotides
language:en
Short-container-title:Oligonucleotides

Author:

Cutrona Giovanna¹,Boffa Lidia C.¹,Mariani Maria Rita¹,Matis Serena¹²,Damonte Gianluca³,Millo Enrico³,Roncella Silvio⁴,Ferrarini Manlio¹²

Affiliation:

1. SC. Oncologia Medica C, Istituto Nazionale per la Ricerca sul Cancro, IST, Genova, Italy.

2. DOBIG, Biochemistry Section, and Center of Excellence for Biomedical Research, Università degli Studi di Genova, Genova, Italy.

3. DIMES, Biochemistry Section, and Center of Excellence for Biomedical Research, Università degli Studi di Genova, Genova, Italy.

4. Anatomic Pathology Unit, Molecular Biology Section, S. Bartolomeo Hospital, Sarzana, SP, Italy.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/oli.2007.9999

Reference10 articles.

1. Therapeutically Promising PNA Complementary to a Regulatory Sequence for c-myc:Pharmacokinetics in an Animal Model of Human Burkitt's Lymphoma

2. Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc

3. Lack of mutagenicity and clastogenicity of PNAEμ-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma

4. Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal

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