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Lack of mutagenicity and clastogenicity of PNAEμ-NLS targeted to a regulatory sequence of the translocated c-myc oncogene in Burkitt's lymphoma

  • Published:2007-04 Issue:2 Volume:628 Page:129-137
  • ISSN:1383-5718
  • Container-title:Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  • language:en
  • Short-container-title:Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Author:

Boffa L.C.,Menichini P.,Bolognesi C.,Cutrona G.,Roncella S.,Damonte G.L.,Millo E.,Mariani M.R.,Matis S.,Russo D.,Ciliutti P.,Ferrarini M.

Publisher

Elsevier BV

Subject

Health, Toxicology and Mutagenesis,Genetics

Reference17 articles.

1. Peptide nucleic acid targeting of double-stranded DNA;Nielsen;Methods Enzymol.,2001

2. Effects in live cells of a c-myc anti-gene PNA linked to a nuclear localization signal;Cutrona;Nat. Biotech.,2000

3. Transcriptional enhancers and the evolution of the IgH locus;Magor;Immunol. Today,1999

4. Inhibition of the translocated c-myc in Burkitt's lymphoma by a PNA complementary to the Eμ enhancer;Cutrona;Cancer Res.,2003

5. Inhibition of Burkitt's lymphoma cells growth in SCID mice by a PNA specific for a regulatory sequence of the translocated c-myc;Boffa;Cancer Gene Ther.,2007
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