Local Administration of the Poly(ADP-Ribose) Polymerase Inhibitor INO-1001 Prevents NAD+ Depletion and Improves Water Maze Performance after Traumatic Brain Injury in Mice-Reference-Cited by-同舟云学术

Local Administration of the Poly(ADP-Ribose) Polymerase Inhibitor INO-1001 Prevents NAD+ Depletion and Improves Water Maze Performance after Traumatic Brain Injury in Mice

Published:2007-08 Issue:8 Volume:24 Page:1399-1405
ISSN:0897-7151
Container-title:Journal of Neurotrauma
language:en
Short-container-title:Journal of Neurotrauma

Author:

Clark Robert S.B.¹²,Vagni Vincent A.¹,Nathaniel Paula D.¹,Jenkins Larry W.³,Dixon C. Edward³,Szabó Csaba⁴

Affiliation:

1. Department of Critical Care Medicine, the Safar Center for Resuscitation Research and the Brain Trauma Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

2. Department of Pediatrics, the Safar Center for Resuscitation Research and the Brain Trauma Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

3. Department of Neurological Surgery, the Safar Center for Resuscitation Research and the Brain Trauma Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

4. Department of Surgery, University of Medicine and Dentistry of New Jersey, Newark, New Jersey.

Publisher

Mary Ann Liebert Inc

Subject

Clinical Neurology

Link

http://www.liebertpub.com/doi/pdf/10.1089/neu.2007.0305

Reference22 articles.

1. Stereological estimation of the total number of neurons in the murine hippocampus using the optical disector

2. Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat

3. Long-Term Memory Requires PolyADP-ribosylation

4. Intra-mitochondrial Poly(ADP-ribosylation) Contributes to NAD+ Depletion and Cell Death Induced by Oxidative Stress

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