Trough Insulin Levels in Bronchoalveolar Lavage Following Inhaled Human Insulin (Exubera) in Patients with Diabetes Mellitus-Reference-Cited by-同舟云学术

Trough Insulin Levels in Bronchoalveolar Lavage Following Inhaled Human Insulin (Exubera) in Patients with Diabetes Mellitus

Published:2012-01 Issue:1 Volume:14 Page:50-58
ISSN:1520-9156
Container-title:Diabetes Technology & Therapeutics
language:en
Short-container-title:Diabetes Technology & Therapeutics

Author:

Mendivil Carlos O.¹²,Teeter John G.³,Finch Gregory L.³,Schwartz Pamela F.³,Riese Richard J.³,Brain Joseph D.¹

Affiliation:

1. Molecular and Integrative Physiological Sciences Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts.

2. University of the Andes Medical School, Bogotá, Colombia.

3. Pfizer Global Research and Development, Groton, Connecticut.

Publisher

Mary Ann Liebert Inc

Subject

Medical Laboratory Technology,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://www.liebertpub.com/doi/pdf/10.1089/dia.2011.0148

Reference37 articles.

1. Inhaling medicines: delivering drugs to the body through the lungs

2. Unlocking the opportunity of tight glycaemic control. Innovative delivery of insulin via the lung

3. Inhaled insulin1Abbreviations: DM, diabetes mellitus; AIDs, acquired immune deficiency syndrome; SC, subcutaneous; DCCT, Diabetes Control and Complications Trial; IDDM, insulin-dependent diabetes mellitus; NIDDM, non-insulin-dependent diabetes mellitus; i.v., intravenous; DDPC, di-decanoyl-alpha-phosphatidylcholine; AUC, area under the curve; INH, inhaled; Cmax, maximum serum concentration; Cmin, minimum serum concentration; Tmax, time of maximum serum concentration; NS, not significant; HbA1c, hemoglobin A1c; OA, oral agent; SD, standard deviation; MDI, metered dose inhaler; DPI, dry powder inhaler; MMAD, mass median aerodynamic diameter; CMC, critical micelle concentration; SR, sustained release; PLGA, poly lactic acid-co-glycolic acid; GI, gastrointestinal, GSD, geometric standard deviation; TLC, total lung capacity; VC, vital capacity; SMK, smokers; MW, molecular weight; MP, melting point.1

4. Time-Action Profile of Inhaled Insulin in Comparison With Subcutaneously Injected Insulin Lispro and Regular Human Insulin

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1. Response to paper by Singh et al. “Hyperinsulinemia adversely affects lung structure and function”;American Journal of Physiology-Lung Cellular and Molecular Physiology;2016-07-01

2. Future prospect of insulin inhalation for diabetic patients: The case of Afrezza versus Exubera;Journal of Controlled Release;2015-10

3. Metabolic Hormones, Apolipoproteins, Adipokines, and Cytokines in the Alveolar Lining Fluid of Healthy Adults: Compartmentalization and Physiological Correlates;PLOS ONE;2015-04-07

4. Newer devices and improved formulations of inhaled insulin;Expert Opinion on Drug Delivery;2014-12-08