Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing-Reference-Cited by-同舟云学术

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Dimeric CRISPR RNA-Guided FokI-dCas9 Nucleases Directed by Truncated gRNAs for Highly Specific Genome Editing

Published:2015-07 Issue:7 Volume:26 Page:425-431
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Wyvekens Nicolas¹²,Topkar Ved V.¹²,Khayter Cyd¹²,Joung J. Keith¹²³,Tsai Shengdar Q.¹²³

Affiliation:

1. Molecular Pathology Unit & Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts.

2. Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts.

3. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2015.084

Reference26 articles.

1. CRISPR-Cas systems for editing, regulating and targeting genomes

2. The new frontier of genome engineering with CRISPR-Cas9

3. Development and Applications of CRISPR-Cas9 for Genome Engineering

4. A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity

5. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

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1. CRISPR/Cas9 as a Mutagenic Factor;International Journal of Molecular Sciences;2024-01-09

2. CRISPR-Cas9: chronology and evolution;CRISPR-Cas System in Translational Biotechnology;2024

3. Anti-CRISPR proteins: a weapon of phage-bacterial arm race for genome editing;The Nucleus;2023-12-15

4. CRISPR/Cas9 Landscape: Current State and Future Perspectives;International Journal of Molecular Sciences;2023-11-08

5. A cleavage rule for selection of increased-fidelity SpCas9 variants with high efficiency and no detectable off-targets;Nature Communications;2023-09-16

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