A New Role for the Nonpathogenic Nonsynonymous Single-Nucleotide Polymorphisms of Acetylcholinesterase in the Treatment of Alzheimer's Disease: A Computational Study
Author:
Affiliation:
1. Department of Biotechnology, School of Biotechnology and Genetic Engineering, Bharathiar University, Coimbatore, Tamil Nadu, India.
Publisher
Mary Ann Liebert Inc
Subject
Computational Theory and Mathematics,Computational Mathematics,Genetics,Molecular Biology,Modeling and Simulation
Link
http://www.liebertpub.com/doi/pdf/10.1089/cmb.2014.0005
Reference40 articles.
1. The ‘aromatic patch’ of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors
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3. Structures of Human Acetylcholinesterase in Complex with Pharmacologically Important Ligands
4. Variations on a Theme: Cataloging Human DNA Sequence Variation
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