CAR T Cells Generated UsingSleeping BeautyTransposon Vectors and Expanded with an EBV-Transformed Lymphoblastoid Cell Line Display Antitumor ActivityIn VitroandIn Vivo-Reference-Cited by-同舟云学术

CAR T Cells Generated UsingSleeping BeautyTransposon Vectors and Expanded with an EBV-Transformed Lymphoblastoid Cell Line Display Antitumor ActivityIn VitroandIn Vivo

Published:2019-04 Issue:4 Volume:30 Page:511-522
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Chicaybam Leonardo¹²,Abdo Luiza¹,Carneiro Mayra¹,Peixoto Bárbara³,Viegas Mariana¹,de Sousa Priscila¹,Fornazin Márcia C.⁴,Spago Maria C.⁴,Albertoni Laranjeira Angelo Brunelli⁴,de Campos-Lima Pedro O.⁵⁶,Nowill Alexandre⁴,Barros Luciana Rodrigues Carvalho¹,Bonamino Martín H.¹²

Affiliation:

1. Molecular Carcinogenesis Program, National Cancer Institute (INCA), Rio de Janeiro, Brazil

2. Vice-Presidency of Research and Biological Collections, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

3. Cell Biology Program, National Cancer Institute (INCA), Rio de Janeiro, Brazil

4. Integrated Center for Oncohematology Research in Infancy, Institute of Biology, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil

5. Institute of Molecular and Cellular Engineering, Boldrini Children's Center, Campinas, Sao Paulo, Brazil.

6. Functional and Molecular Biology Program, Institute of Biology, University of Campinas (UNICAMP), Campinas, Sao Paulo, Brazil

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2018.218

Reference45 articles.

1. Efficiency of CD19 chimeric antigen receptor-modified T cells for treatment of B cell malignancies in phase I clinical trials: a meta-analysis

2. Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

3. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

4. Retroviral vectors and transposons for stable gene therapy: advances, current challenges and perspectives

5. Insertional Transformation of Hematopoietic Cells by Self-inactivating Lentiviral and Gammaretroviral Vectors

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