An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy-Reference-Cited by-同舟云学术

An Early Wave of Macrophage Infiltration Intertwined with Antigen-Specific Proinflammatory T Cells and Browning of Adipose Tissue Characterizes the Onset of Orbital Inflammation in a Mouse Model of Graves' Orbitopathy

Published:2022-01-11 Issue: Volume: Page:
ISSN:1050-7256
Container-title:Thyroid
language:en
Short-container-title:Thyroid

Author:

Philipp Svenja¹^ORCID,Horstmann Mareike¹,Hose Matthias²,Daser Anke³,Görtz Gina-Eva¹,Jesenek Christoph⁴,Flögel Ulrich⁵,Hansen Wiebke²,Bechrakis Nikolaos¹⁶^ORCID,Banga Jasvinder Paul S.¹,Eckstein Anja¹,Berchner-Pfannschmidt Utta¹

Affiliation:

1. Molecular Ophthalmology, Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

2. Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

3. Department of Oto-Rhino-Laryngology, Head and Neck Surgery, and University Hospital Essen, University Duisburg-Essen, Essen, Germany.

4. Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

5. Experimental Cardiovascular Imaging, Department of Molecular Cardiology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.

6. Department of Ophthalmology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

Publisher

Mary Ann Liebert Inc

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Link

https://www.liebertpub.com/doi/pdf/10.1089/thy.2021.0464

Reference38 articles.

1. Graves’ disease

2. Current perspectives on the role of orbital fibroblasts in the pathogenesis of Graves' ophthalmopathy

3. TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis