A Lower Viral Set Point but Little Immunological Impact After Early Treatment During Primary HIV Infection-Reference-Cited by-同舟云学术

A Lower Viral Set Point but Little Immunological Impact After Early Treatment During Primary HIV Infection

Published:2015-04 Issue:3 Volume:28 Page:134-144
ISSN:0882-8245
Container-title:Viral Immunology
language:en
Short-container-title:Viral Immunology

Author:

Spits Hilde B.¹,Grijsen Marlous L.²,Steingrover Radjin²³,Nanlohy Nening M.¹,Kootstra Neeltje⁴,Borghans José A.M.¹,van Baarle Debbie¹⁵,Prins Jan M.²,Schellens Ingrid M.M.¹⁵

Affiliation:

1. Laboratory of Translational Immunology, Department of Immunology, University Medical Center Utrecht, Utrecht, the Netherlands.

2. Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam (CINIMA), University of Amsterdam, Amsterdam, the Netherlands.

3. Department of Global Health, Amsterdam Institute for Global Health and Development, University of Amsterdam, Amsterdam, the Netherlands.

4. Department of Experimental Immunology, CINIMA, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.

5. Department of Internal Medicine and Infectious Diseases, University Medical Center Utrecht, Utrecht, the Netherlands.

Publisher

Mary Ann Liebert Inc

Subject

Virology,Molecular Medicine,Immunology

Link

https://www.liebertpub.com/doi/pdf/10.1089/vim.2014.0094

Reference35 articles.

1. Superior control of HIV-1 replication by CD8+ T cells is reflected by their avidity, polyfunctionality, and clonal turnover

2. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells

3. Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection

4. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

5. Microbial translocation is a cause of systemic immune activation in chronic HIV infection

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