Proinsulin Slows Retinal Degeneration and Vision Loss in the P23H Rat Model of Retinitis Pigmentosa-Reference-Cited by-同舟云学术

Proinsulin Slows Retinal Degeneration and Vision Loss in the P23H Rat Model of Retinitis Pigmentosa

Published:2012-12 Issue:12 Volume:23 Page:1290-1300
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Fernández-Sánchez Laura¹,Lax Pedro¹,Isiegas Carolina²,Ayuso Eduard³,Ruiz José M.²,de la Villa Pedro⁴,Bosch Fatima³,de la Rosa Enrique J.⁵,Cuenca Nicolás¹⁶

Affiliation:

1. Department of Physiology, Genetics and Microbiology, University of Alicante, E-03080 Alicante, Spain.

2. ProRetina Therapeutics SL, Centro de Investigaciones Biologicas and CEIN, E-28040 Madrid and E-31110 Noain, Spain.

3. Center of Animal Biotechnology and Gene Therapy and Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.

4. Department of Physiology, School of Medicine, University of Alcalá, Alcalá de Henares, E-28801 Madrid, Spain.

5. 3D Lab (Development, Differentiation and Degeneration), Department of Cellular and Molecular Medicine, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, 28040 Madrid, Spain.

6. Multidisciplinary Institute for Environmental Studies “Ramon Margalef”, University of Alicante, E-03080 Alicante, Spain.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2012.067

Reference65 articles.

1. Decreased glutathione transferase levels in rd1/rd1 mouse retina: Replenishment protects photoreceptors in retinal explants

2. High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency

3. Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis

4. Ocular Findings in Patients With Autosomal Dominant Retinitis Pigmentosa and a Rhodopsin Gene Defect (Pro-23-His)

5. A Randomized Trial of Vitamin A and Vitamin E Supplementation for Retinitis Pigmentosa

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