High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis-Reference-Cited by-同舟云学术

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High-Content, Full Genome siRNA Screen for Regulators of Oncogenic HRAS-Driven Macropinocytosis

Published:2015-09 Issue:7 Volume:13 Page:347-355
ISSN:1540-658X
Container-title:ASSAY and Drug Development Technologies
language:en
Short-container-title:ASSAY and Drug Development Technologies

Author:

Fennell Myles¹,Commisso Cosimo²,Ramirez Craig³,Garippa Ralph¹,Bar-Sagi Dafna³

Affiliation:

1. RNAi and Gene Editing Core Facility, Memorial Sloan-Kettering Cancer Center, New York, New York.

2. NCI-Designated Cancer Center Cell Death and Survival Networks Program, Sanford-Burnham Medical Research Institute, La Jolla, California.

3. Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/adt.2015.660

Reference26 articles.

1. KRAS, Hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma

2. Presence of Somatic Mutations in Most Early-Stage Pancreatic Intraepithelial Neoplasia

3. Defining Macropinocytosis

4. Induction of Membrane Ruffling and Fluid-Phase Pinocytosis in Quiescent Fibroblasts by ras Proteins

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1. Impact of Oncogenic Changes in p53 and KRAS on Macropinocytosis and Ferroptosis in Colon Cancer Cells and Anticancer Efficacy of Niclosamide with Differential Effects on These Two Processes;Cells;2024-05-30

2. ATP2B4 is an essential gene for epidermal growth factor‐induced macropinocytosis in A431 cells;Genes to Cells;2024-04-10

3. Cell polarity proteins promote macropinocytosis in response to metabolic stress;2024-01-20

4. NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma;Cancer Communications;2023-12-28

5. Cytoskeletal association of ATP citrate lyase controls the mechanodynamics of macropinocytosis;Proceedings of the National Academy of Sciences;2023-02-14

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