Development and Application of a High-Throughput Fluorescence Polarization Assay to Target Pim Kinases
Author:
Affiliation:
1. Department of Chemistry, Keimyung University, Daegu, Korea.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2015.685
Reference32 articles.
1. For better or for worse: the role of Pim oncogenes in tumorigenesis
2. The PIM Family of Serine/Threonine Kinases in Cancer
3. PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
4. Structural Basis of Constitutive Activity and a Unique Nucleotide Binding Mode of Human Pim-1 Kinase
5. Pan-PIM Kinase Inhibition Provides a Novel Therapy for Treating Hematologic Cancers
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1. Identification and Kinetic Characterization of Serum- and Glucocorticoid-Regulated Kinase Inhibitors Using a Fluorescence Polarization–Based Assay;SLAS DISCOVERY: Advancing the Science of Drug Discovery;2021-03-30
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3. Homogeneous peptide-break assay for luminescent detection of enzymatic protein post-translational modification activity utilizing charged peptides;Analytica Chimica Acta;2019-05
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