Cytochrome P450 Genotyping by Multiplexed Real-Time DNA Sequencing with Pyrosequencing™ Technology
Author:
Affiliation:
1. Pyrosequencing AB, Uppsala, Sweden
2. Department of Medical Sciences, Clinical Pharmacology, Uppsala University, Uppsala, Sweden
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/154065802761001301
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3. Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution
4. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.
5. Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of theCYP2D6gene
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