Ultrarapid metabolizers of debrisoquine: Characterization and PCR-based detection of alleles with duplication of theCYP2D6gene
Author:
Publisher
Wiley
Subject
Cell Biology,Genetics,Molecular Biology,Biochemistry,Structural Biology,Biophysics
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1016/0014-5793(96)00779-X/fullpdf
Reference25 articles.
1. The role of individual human cytochrpmes P450 in drug metabolism and clinical response
2. A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.
3. Clinical significance of the sparteine/debrisoquine oxidation polymorphism
4. Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.
5. Genetic and metabolic criteria for the assignment of debrisoquine 4-hydroxylation (cytochrome P4502D6) phenotypes
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