Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.-Reference-Cited by-同舟云学术

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.

Published:1990-10 Issue:28 Volume:265 Page:17209-17214
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

Kagimoto M,Heim M,Kagimoto K,Zeugin T,Meyer U A

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference29 articles.

1. The genetic polymorphism of debrisoquine/sparteine metabolism—molecular mechanisms

2. Ethnic Differences in Reactions to Drugs and Xenobiotics;Kalow,1986

3. Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

4. Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Cited by 155 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The genomic landscape of CYP2D6 variation in the Indian population;Pharmacogenomics;2024-02

2. G-quadruplex forming sequences in the genes coding for cytochrome P450 enzymes and their potential roles in drug metabolism;Biochimie;2023-11

3. Pharmacogenomics in Psychiatric Diseases;Pharmacogenomics in Clinical Practice;2023

4. Genetic Biomarkers of Antipsychotic-Induced Prolongation of the QT Interval in Patients with Schizophrenia;International Journal of Molecular Sciences;2022-12-13

5. Recognition of functional genetic polymorphism using ESE motif definition: a conservative evolutionary approach to CYP2D6/CYP2C19 gene variants;Genetica;2022-08-01