A High-Throughput Screening Assay for NKCC1 Cotransporter Using Nonradioactive Rubidium Flux Technology
Author:
Affiliation:
1. Aurora Biomed Inc., Vancouver, Canada.
2. Roche Innovation Center Basel, Hoffmann-La Roche, Basel, Switzerland.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2017.787
Reference30 articles.
1. Ion Transporters in Brain Tumors
2. NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension
3. High-throughput fluorescent-based NKCC functional assay in adherent epithelial cells
4. Mutagenic Mapping of the Na-K-Cl Cotransporter for Domains Involved in Ion Transport and Bumetanide Binding
5. A Thallium-Sensitive, Fluorescence-Based Assay for Detecting and Characterizing Potassium Channel Modulators in Mammalian Cells
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