High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter-Reference-Cited by-同舟云学术

High-Level Transduction and Gene Expression in Hematopoietic Repopulating Cells Using a Human Imunodeficiency Virus Type 1-Based Lentiviral Vector Containing an Internal Spleen Focus Forming Virus Promoter

Published:2002-05 Issue:7 Volume:13 Page:803-813
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Demaison Christophe¹,Parsley Kathryn¹,Brouns Gaby¹,Scherr Michaela²,Battmer Karin²,Kinnon Christine¹,Grez Manuel³,Thrasher Adrian J.¹

Affiliation:

1. Molecular Immunology Unit, Institute of Child Health, UCL, London, WC1N 1EH, UK

2. Department of Hematology, Medical School Hannover, 30625 Germany

3. Georg-Speyer-Haus, Frankfurt, 60596 Germany

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/10430340252898984

Reference50 articles.

1. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

2. Marking and Gene Expression by a Lentivirus Vector in Transplanted Human and Nonhuman Primate CD34 + Cells

3. Novel retroviral vectors for efficient expression of the multidrug resistance (mdr-1) gene in early hematopoietic cells

4. The potent enhancer activity of the polycythemic strain of spleen focus-forming virus in hematopoietic cells is governed by a binding site for Sp1 in the upstream control region and by a unique enhancer core motif, creating an exclusive target for PEBP/CBF

5. Correction of Respiratory Burst Activity in X-Linked Chronic Granulomatous Cells to Therapeutically Relevant Levels after Gene Transfer into Bone Marrow CD34+Cells

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