1. School of Health and Related Medicine, University of Sheffield, Sheffield, United Kingdom.
2. Academic Unit of Medical Genetics, St. Mary's Hospital, Manchester, United Kingdom.
3. Department of Genetic Medicine, St. Mary's Hospital, Manchester, United Kingdom.
4. Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
5. Health Sciences—Economics, School of Community Based Medicine, University of Manchester, Manchester, United Kingdom.