Drug Repositioning for Amyloid Transthyretin Amyloidosis by Interactome Network Corrected by Graph Neural Networks and Transcriptome Analysis-Reference-Cited by-同舟云学术

Drug Repositioning for Amyloid Transthyretin Amyloidosis by Interactome Network Corrected by Graph Neural Networks and Transcriptome Analysis

Published:2024-01-01 Issue:1-2 Volume:35 Page:70-79
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

He Shan¹,Lv XiaoYing²,He XinYue¹,Guo JinJiang²,Pan RuoKai¹,Jin YuTong²,Tian Zhuang¹,Pan LuRong²,Zhang ShuYang¹

Affiliation:

1. Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

2. Global Health Drug Discovery Institute, Beijing, China.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

https://www.liebertpub.com/doi/pdf/10.1089/hum.2021.222

Reference45 articles.

1. The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

2. Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments

3. Recent progress in the understanding and treatment of transthyretin amyloidosis

4. A prospective evaluation of the transthyretin Ile122 allele frequency in an African-American population

5. Variant-Sequence Transthyretin (Isoleucine 122) in Late-Onset Cardiac Amyloidosis in Black Americans

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