Simultaneous Knockout ofCXCR4andCCR5Genes in CD4+ T Cells via CRISPR/Cas9 Confers Resistance to Both X4- and R5-Tropic Human Immunodeficiency Virus Type 1 Infection-Reference-Cited by-同舟云学术

Simultaneous Knockout ofCXCR4andCCR5Genes in CD4+ T Cells via CRISPR/Cas9 Confers Resistance to Both X4- and R5-Tropic Human Immunodeficiency Virus Type 1 Infection

Published:2018-01 Issue:1 Volume:29 Page:51-67
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Yu Songlin¹,Yao Yongchao¹²³,Xiao Hongkui⁴,Li Jiaojiao⁴,Liu Quan¹,Yang Yijun¹,Adah Dickson¹,Lu Junnan¹,Zhao Siting¹,Qin Li¹,Chen Xiaoping¹

Affiliation:

1. Laboratory of Pathogen Biology, State Key Laboratory of Respiratory Disease, Center for Infection and Immunity, Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences, Guangzhou, China

2. Shenzhen Geriatric Research Institute, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Shenzhen, China

3. The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

4. School of Life Sciences, Anhui University, Hefei, China.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2017.032

Reference54 articles.

1. CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1

2. Identification of a major co-receptor for primary isolates of HIV-1