A Sophism in Vectorology: Turning Harmful Defective Retroviral Vectors into Helpful Replication-Competent Retroviruses Against Cancer-Reference-Cited by-同舟云学术

A Sophism in Vectorology: Turning Harmful Defective Retroviral Vectors into Helpful Replication-Competent Retroviruses Against Cancer

Published:2017-11 Issue:11 Volume:28 Page:954-957
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Klatzmann David¹²

Affiliation:

1. Sorbonne Université, University Pierre and Marie Curie (UPMC), Univ Paris 06, INSERM, UMR_S 959, Immunology-Immunopathology-Immunotherapy (i3), Paris, France

2. AP-HP (Assistance Publique–Hôpitaux de Paris), Hôpital Pitié-Salpêtrière, Biotherapy (CIC-BTi), and Inflammation-Immunopathology-Biotherapy Department (i2B), Paris, France.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2017.29050.dkl

Reference22 articles.

1. Gene Therapy for Glioblastoma in Adult Patients: Safety and Efficacy Evaluation of an In Situ Injection of Recombinant Retroviruses Producing Cells Carrying the Thymidine Kinase Gene of the Herpes Simplex Type 1 Virus, to be Followed with the Administration of Ganciclovir. Laboratoire Immunologie B, Hôpital Pitié-Salpêtrière, Paris Cedex, France

2. Gene Therapy for Metastatic Malignant Melanoma: Evaluation of Tolerance to Intratumoral Injection of Cells Producing Recombinant Retroviruses Carrying the Herpes Simplex Virus Type 1 Thymidine Kinase Gene, to be Followed by Ganciclovir Administration. Laboratoire Immunologie B, Hôpital Pitié-Salpêtrière, Paris Cedex, France

3. In Vivo Gene Transfer with Retroviral Vector-Producer Cells for Treatment of Experimental Brain Tumors

4. Regression of established macroscopic liver metastases after in situ transduction of a suicide gene.