Gene Therapy for Glioblastoma in Adult Patients: Safety and Efficacy Evaluation of an In Situ Injection of Recombinant Retroviruses Producing Cells Carrying the Thymidine Kinase Gene of the Herpes Simplex Type 1 Virus, to be Followed with the Administration of Ganciclovir. Laboratoire Immunologie B, Hôpital Pitié-Salpêtrière, Paris Cedex, France-Reference-Cited by-同舟云学术

Gene Therapy for Glioblastoma in Adult Patients: Safety and Efficacy Evaluation of an In Situ Injection of Recombinant Retroviruses Producing Cells Carrying the Thymidine Kinase Gene of the Herpes Simplex Type 1 Virus, to be Followed with the Administration of Ganciclovir. Laboratoire Immunologie B, Hôpital Pitié-Salpêtrière, Paris Cedex, France

Published:1996-01 Issue:1 Volume:7 Page:109-126
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Klatzmann David¹,Philippon Jacques²,Valery Charles A.²,Bensimon Gilbert³,Salzmann Jean-Loup⁴

Affiliation:

1. Laboratoire de Biologie et Thérapeutique des Pathologies Immunitaires, Hôpital de la Pitié-Salpêtrière, Université Pierre et Marie Curie, CNRS URA 1463, CERVI, 83 bd de l'Hôpital, 75651 Paris cedex 13

2. Service de Neuro-Chirurgie, Hôpital Pitié-Salpêtrière

3. Départment de Pharmacologie Clinique, Division Ambroise Paré, Service du Pr. A.J. Puech, Hôpital de la Pitié-Salpêtrière, 47 bd de L'Hôpital, 75651 Paris cedex 13

4. Service d'Histo-Embryologie, Hôpital Avicenne, 125 Route de Stalingrad, 93009 Bobigny cedex

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.1996.7.1-109

Reference13 articles.

1. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas

2. A randomized comparison of intra-arterial versus intravenous with or without intravenous 5-fluorouracil, for newly diagnosed patients with malignant glioma

3. Cell kinetics of human gliomas

4. The biochemistry and mechanism of action of acyclovir

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