Ultra-High-Throughput Screening for Antagonists of A Gi-Coupled Receptor in A 2.2-μl 3,456-Well Plate Format CyclicAMP Assay
Author:
Affiliation:
1. Department of Automated Biotechnology, Merck Research Laboratories, North Wales, PA.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/adt.2006.043
Reference5 articles.
1. Hit and lead generation: beyond high-throughput screening
2. G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS
3. cAMP detection methods in HTS: selecting the best from the rest
4. A 1,536-Well cAMP Assay for Gs- and Gi-Coupled Receptors Using Enzyme Fragmentation Complementation
5. Miniaturization of Whole Live Cell-Based GPCR Assays Using Microdispensing and Detection Systems
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