Compacted DNA Nanoparticles Administered to the Nasal Mucosa of Cystic Fibrosis Subjects Are Safe and Demonstrate Partial to Complete Cystic Fibrosis Transmembrane Regulator Reconstitution
Author:
Affiliation:
1. Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH 44106.
2. Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80218.
3. Copernicus Therapeutics, Cleveland, OH 44106.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2004.15.1255
Reference79 articles.
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3. Expression of the cystic fibrosis transmembrane conductance regulator gene can be regulated by protein kinase C.
4. Interferon-gamma downregulates CFTR gene expression in epithelial cells
5. Status of gene therapy for cystic fibrosis lung disease
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