1. Department of Pharmacy, Federal University of Paraná, Curitiba, Brazil.
2. Department of Pharmacology, Federal University of Paraná, Curitiba, Brazil.
3. Department of Pharmaceutical Sciences, State University of Ponta Grossa, Ponta Grossa, Brazil.
4. Brazilian Agricultural Research Corporation, Embrapa Pantanal, Corumbá, Brazil.
5. Institute of Botany, São Paulo, Brazil.
6. Department of Chemistry, Federal University of Paraná, Curitiba, Brazil.