Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1

Author:

Luo Meihua1,Delaplane Sarah2,Jiang Aihua3,Reed April1,He Ying1,Fishel Melissa1,Nyland Rodney L.4,Borch Richard F.4,Qiao Xiaoxi3,Georgiadis Millie M.2,Kelley Mark R.125

Affiliation:

1. Department of Pediatrics (Section of Hematology/Oncology), Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.

2. Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana.

3. Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana.

4. Department of Medicinal Chemistry and Molecular Pharmacology and Cancer Center, Purdue University, West Lafayette, Indiana.

5. Department of Pharmacology & Toxicology, Indiana University School of Medicine, Indianapolis, Indiana.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

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