Low Frequency of Protease Inhibitor Resistance Mutations and Insertions in HIV-1 Subtype C Protease Inhibitor-Naïve Sequences-Reference-Cited by-同舟云学术

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Low Frequency of Protease Inhibitor Resistance Mutations and Insertions in HIV-1 Subtype C Protease Inhibitor-Naïve Sequences

Published:2019-07 Issue:7 Volume:35 Page:673-678
ISSN:0889-2229
Container-title:AIDS Research and Human Retroviruses
language:en
Short-container-title:AIDS Research and Human Retroviruses

Author:

Ledwaba Johanna¹,Sayed Yasien²,Pillay Visva¹,Morris Lynn¹³,Hunt Gillian¹³

Affiliation:

1. Centre for HIV and STIs, National Institute for Communicable Diseases, Johannesburg, South Africa.

2. Protein Structure-Function Research Unit, School of Molecular and Cell Biology, University of the Witwatersrand, Johannesburg, South Africa.

3. Department of Virology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Publisher

Mary Ann Liebert Inc

Subject

Infectious Diseases,Virology,Immunology

Link

https://www.liebertpub.com/doi/pdf/10.1089/aid.2019.0012

Reference28 articles.

1. HIV-1 protease: mechanism and drug discovery

2. HIV-1 Protease, Reverse Transcriptase, and Integrase Variation

3. Molecular Characteristics of Human Immunodeficiency Virus Type 1 Subtype C Viruses from KwaZulu-Natal, South Africa: Implications for Vaccine and Antiretroviral Control Strategies

4. Catalytic efficiency and vitality of HIV-1 proteases from African viral subtypes

5. Structural insights into the South African HIV-1 subtype C protease: impact of hinge region dynamics and flap flexibility in drug resistance

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanism of drug resistance in HIV-1 protease subtype C in the presence of Atazanavir;Current Research in Structural Biology;2024

2. HIV Protease Hinge Region Insertions at Codon 38 Affect Enzyme Kinetics, Conformational Stability and Dynamics;The Protein Journal;2023-07-08

3. Understanding Drug Resistance of Wild-Type and L38HL Insertion Mutant of HIV-1 C Protease to Saquinavir;Genes;2023-02-20

4. Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview;AIDS Research and Therapy;2021-01-06

5. High nonnucleoside reverse transcriptase inhibitor resistance levels in HIV-1-infected Zambian mother–infant pairs;AIDS;2020-07-23

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