Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids-Reference-Cited by-同舟云学术

Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids

Published:2020-11-10 Issue:14 Volume:33 Page:1003-1009
ISSN:1523-0864
Container-title:Antioxidants & Redox Signaling
language:en
Short-container-title:Antioxidants & Redox Signaling

Author:

Costa Soraia K.P.F.¹,Muscara Marcelo N.¹,Allain Thibault²,Dallazen Jorge¹,Gonzaga Larissa¹,Buret Andre G.²,Vaughan David J.³,Fowler Christopher J.⁴,de Nucci Gilberto⁵,Wallace John L.³⁵⁶

Affiliation:

1. Department of Pharmacology, Institute of Biomedical Sciences, University of Sao Paulo, São Paulo, Brazil.

2. Department of Biological Sciences, University of Calgary, Alberta, Canada.

3. Antibe Therapeutics, Inc., Toronto, Canada.

4. Department of Pharmacology and Clinical Neuroscience, Umeå University, Umeå, Sweden.

5. Department of Pharmacology, University of Campinas, Campinas, Brazil.

6. Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry,Cell Biology,Clinical Biochemistry,Molecular Biology,Physiology,Biochemistry

Link

https://www.liebertpub.com/doi/pdf/10.1089/ars.2019.7884

Reference37 articles.

1. AP39, A Mitochondrially Targeted Hydrogen Sulfide Donor, Exerts Protective Effects in Renal Epithelial Cells Subjected to Oxidative Stress in Vitro and in Acute Renal Injury in Vivo

2. Characterization of a rat model of incisional pain

3. A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice

4. 5-Amino-2-hydroxybenzoic Acid 4-(5-Thioxo-5H-[1,2]dithiol-3yl)-phenyl Ester (ATB-429), a Hydrogen Sulfide-Releasing Derivative of Mesalamine, Exerts Antinociceptive Effects in a Model of Postinflammatory Hypersensitivity

5. Efficient Analysis of Experimental Observations

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