A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice-Reference-Cited by-同舟云学术

A novel orally administered trimebutine compound (GIC-1001) is anti-nociceptive and features peripheral opioid agonistic activity and Hydrogen Sulphide-releasing capacity in mice

Published:2015-11-06 Issue:5 Volume:20 Page:723-730
ISSN:1090-3801
Container-title:European Journal of Pain
language:en
Short-container-title:Eur J Pain

Author:

Cenac N.¹²³,Castro M.¹²³,Desormeaux C.¹²³,Colin P.⁴,Sie M.¹²³,Ranger M.⁴,Vergnolle N.¹²³⁵

Affiliation:

1. INSERM U1043; Toulouse France

2. CNRS U5282; Toulouse France

3. Centre de Physiopathologie de Toulouse Purpan (CPTP); Université de Toulouse, Université Paul Sabatier; France

4. GIcare pharma Inc; Montréal Canada

5. Department of Physiology and Pharmacology; University of Calgary; Canada

Funder

GICare pharma Inc.

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ejp.798/fullpdf

Reference25 articles.

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3. Current and future pharmacological treatments for diarrhea-predominant irritable bowel syndrome;Camilleri;Expert Opin Pharmacother,2013

4. Role for protease activity in visceral pain in irritable bowel syndrome;Cenac;J Clin Invest,2007

5. Histamine and serotonin sensitizes the transient receptor potential vanilloid receptor 4 to induce visceral allodynia and hyperalgesia;Cenac;Gastroenterology,2008

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